IFCC Network for Standardization of HbA1c

Welcome to the website of the IFCC Network for Standardization of HbA1c

The purpose of the IFCC Network for Standardization of HbA1c is to standardize HbA1c test results of routine methods to the IFCC Reference Measurement Procedure.

Diabetes Mellitus has become a worldwide epidemic, affecting 400 million people. Effective and efficient monitoring of diabetic control and diagnosis requires a good marker for estimation of the average blood glucose over a longer period. HbA1c meets this requirement for such a reliable compass to guide therapy.
For optimal clinical use (e.g. uniform clinical guidelines, uniform reference values, comparison of scientific studies) equivalence of results is desirable: results of any laboratory anywhere in the world and irrespective the routine method used, should be the same. This requires standardization. The IFCC Reference Measurement Procedure for HbA1c is the analytical anchor for the worldwide standardization of all routine HbA1c assays.
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NEWS: EurA1c

Results of the first EurA1c trial, the European HbA1c Trial to investigate the performance of HbA1c assays in 2166 laboratories across 17 Countries and 24 Manufacturers by use of the IFCC model for quality targets has recently been published in Clin Chem 2018;64:1183-92. The report of the second trial in 2017 is available from the network coordinator. The 2018 trial with more than 4000 laboratories in 25 countries is running from October 2018 to April 2019.