IFCC Network for Standardization of HbA1c

Welcome to the website of the IFCC Network for Standardization of HbA1c

The purpose of the IFCC Network for Standardization of HbA1c is to standardize HbA1c test results of routine methods to the IFCC Reference Measurement Procedure.

Diabetes Mellitus has become a worldwide epidemic, affecting 400 million people. Effective and efficient monitoring of diabetic control and diagnosis requires a good marker for estimation of the average blood glucose over a longer period. HbA1c meets this requirement for such a reliable compass to guide therapy.
For optimal clinical use (e.g. uniform clinical guidelines, uniform reference values, comparison of scientific studies) equivalence of results is desirable: results of any laboratory anywhere in the world and irrespective the routine method used, should be the same. This requires standardization. The IFCC Reference Measurement Procedure for HbA1c is the analytical anchor for the worldwide standardization of all routine HbA1c assays.

EurA1c 2025 and Publication review 9 years EurA1c

The 2025 EurA1c report is released and available on the website. The EurA1c trial that investigates the performance of HbA1c assays across countries and manufacturers was organized for the 10th time in 2025 with participation of more than 4700 laboratories in 21 countries. EurA1c 2026 will be running from October 2026 to April 2027.

With great pleasure I can let you know that the paper “EurA1c: a review of 9 years performance of up to 5120 laboratories in 29 country and 26 manufacturer groups according to current and proposed criteria of the IFCC Model for Quality Targets in relation to the use of HbA 1c for monitoring and diagnosis of diabetes” of the IFCC C-EUBD in collaboration with 29 EQA organizers is published online in Clin Chem Lab Med. Clin Chem Lab Med 2026; 64(8): 1886–1900 https://doi.org/10.1515/cclm-2026-0276